Endocrine Abstracts

Pseudoacromegaly is a rare disorder characterized by cutaneous manifestations of growth hormone excess but with normal growth hormone levels or IGF-1. This condition described in patients with insulin resistance, hypothyroidism, pachydermoperiostitis and drug intake such as minoxidil. The hyperinsulinaemia impaired metabolic signalling may activate intact mitogenic signalling pathways and stimulate pathological tissue growth.A 41-year-old man presented w...

Ectopic thyroid is a rare developmental anomaly of the thyroid gland which is defined as the presence of thyroid tissue at a site other than the pretracheal area. Nearly 1–3% of all ectopic thyroids are located in the lateral neck. Simultaneous submandibular ectopic thyroid tissue presenting with a functional orthotopic thyroid gland is extremely rare. A 37-year-old woman was admitted to our outpatient clinic with a cervical mass existing for 3 years. On physical examinat...

Adrenal metastasis is common (35%) among the patients with lung cancer, while less than 3% of the patients develop bilateral adrenal metastasis. Adrenal metastases are generally small and clinically asymptomatic. Adrenal insufficiency is rare despite the presence of adrenal metastasis. Lam et al. reported this ratio as 0.7%. We aimed to present a case with lung cancer and bilateral adrenal metastasis who developed adrenal insufficiency.A 63-year old male...

Adrenal lymphangioma is a rare benign tumors of the adrenal gland. Because of the increased use of imaging methods in recent times, the diagnosis is usually made incidentally. It is usually due to malformation between the lymphatic and the venous system. Those with small indiameters are generally asymptomatic and can be evacuated by needlea spiration. However, surgery is recommended for cysts over 6 cm in diameter due to risk of infection, bleeding, compression of neighboring ...

Non-islet cell tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome and is the second most common cause of tumor-related hypoglycemia following insulinoma. Its prevalence is not known and is likely that many cases would go undiagnosed. In here, we describe a patient with PNET who presented with severe hypoglycemia.A 37-year-old male with known metastatic Pancreatic neuroendocrine tumors (PNET) presented with weight loss, sweating, and tremor, epi...

Aim: The incidence of nodular thyroid disease is high among patients with insulin resistance. The aim of this study is to evaluate the relationship between BRAFV600E mutation and insulin resistance in the patients with papillary thyroid cancer.Materials and methods: We examined clinical and laboratory data of 103 patients who had been followed up by our department between the years 2010 and 2015. The diagnosis of insulin resistance (IR) was made when the...

Anaplastic thyroid carcinoma (ATC) is one of the most aggressive and lethal human malignancies. The median survival time following diagnosis is typically six months or less. Rapidly growing tumors may cause respiratory failure by compressing trachea. A 71-year-old woman presented with 1-month history of dyspnea, cyanosis and rapidly enlarging neck mass for the past 2 weeks. She had been suffering from multinodular goiter disease. Physical examination revealed a large, fixed an...

Prevalence of Paget’s disease (PD) of bone as well as clinical and demographical presentation may differ between the populations.Aim: In this study we evaluate clinical and demographical parameters of Paget’s disease patients followed from endocrinology clinics in Turkey.Method: An invitation was sent to all tertiary endocrinology clinics to complete a survey on demographic clinical, laboratory parameters, treatment modal...

Pituitary apoplexy (PA) is a rare but life-threatening medical emergency. Common predisposing factors include closed head trauma, blood pressure alterations, history of pituitary irradiation, cardiac surgery, anticoagulation, treatment with dopamine agonists, pituitary stimulation testing, and pregnancy. Hantaviruses belonging to the Bunyaviridae family are a group of rodent- or insectivore-borne single-strand ribonucleic acid (RNA) viruses. In humans, hantaviruses can cause h...

Osteopoikilosis (OPK) is a rare benign sclerotic bone dysplasia. It is inherited in an autosomal dominant pattern. There is no exact evidence of its aetiology and pathogenesis. Usually, it is an asymptomatic disease and the diagnosis is made incidentally from radiographs which show multiple, small, well-defined, variably shaped and widely distributed sclerotic areas over the skeleton. We report a family with OPK. A 22 years old woman was admitted to outpatient clinic with comp...